Centre for Evaluation of Traditional Medicine (TradMed-CoE)

The Centre for Evaluation of Traditional Medicine (TradMed CoE), School of Natural Product Studies, Jadavpur University, is an interdisciplinary research platform dedicated to the scientific validation, safety evaluation, and translational development of traditional medicine systems, particularly Ayurveda. The Centre integrates toxicology, metabolomics, systems biology, and artificial intelligence to build robust evidence frameworks that align classical knowledge with contemporary biomedical science.

TradMed CoE conducts systematic acute, subacute, and chronic toxicological evaluations of selected Ayurvedic herbs and formulations using validated in vivo models, in accordance with CCRAS-aligned guidelines. Its research extends to organ-specific and reproductive toxicity assessments, including detailed haematological, biochemical, and histopathological investigations to identify potential risk factors and ensure regulatory-grade safety profiling.

A major strength of the Centre lies in its metabolomics-driven approach. Using advanced LC-MS/MS and GC-MS platforms, TradMed CoE identifies metabolomic signatures and biomarkers linked to therapeutic outcomes or toxicity. These datasets support predictive toxicology models and help decode formulation behaviour at molecular and pathway levels. Safety pharmacology studies, including CYP450 modulation analysis, further evaluate herb–drug and herb–food interactions affecting cardiovascular, hepatic, renal, and neurological systems.

Moving beyond conventional pharmacology, the Centre applies network pharmacology, systems biology, and AI/ML-based modelling to understand synergistic interactions among phytoconstituents. By mapping metabolite–target–pathway relationships, TradMed CoE seeks to explain how complex Ayurvedic formulations achieve multi-target therapeutic effects. This integrative approach bridges classical Ayurvedic principles such as guna, karma, and prabhava with toxicogenomic and metabolomic datasets, creating a scientifically coherent translational framework.

TradMed CoE is also developing structured digital repositories for Ayurvedic safety and efficacy data to support regulatory science, pharmacovigilance, and future CCRAS research initiatives. Beyond laboratory research, the Centre promotes ethical documentation, chemo-bio profiling, and standardisation of traditional medicinal knowledge systems. It supports advanced natural product research using in vitro and in vivo platforms, fosters disease-prevention and wellness models rooted in traditional healthcare concepts, and develops AI-enabled platforms for predictive modelling and therapeutic discovery.

Within this broader vision, ISE-SFEC-2027 represents a major international outreach initiative of TradMed CoE, extending its translational research philosophy to a global platform. The Congress will amplify dialogue on safety science, metabolomics-guided validation, AI-driven ethnopharmacology, biodiversity governance, and sustainable bioeconomy models.